Assessing Cerebrovascular Resistance in Patients With Sickle Cell Disease

In patients with sickle cell disease (SCD) the delivery of oxygen to the brain is compromised by anemia, abnormal rheology, and steno-occlusive vascular disease. Meeting demands for oxygen delivery requires compensatory features of brain perfusion. The cerebral vasculature’s regulatory function and...

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Bibliographic Details
Main Authors: Ece Su Sayin, Olivia Sobczyk, Julien Poublanc, David J. Mikulis, Joseph A. Fisher, Kevin H. M. Kuo, James Duffin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.847969/full