Rescue of Misfolded Organic Cation Transporter 3 Variants

Rescue of Misfolded Organic Cation Transporter 3 Variants

Organic cation transporters (OCTs) are membrane proteins that take up monoamines, cationic drugs and xenobiotics. We previously reported novel missense mutations of organic cation transporter 3 (OCT3, SLC22A3), some with drastically impacted transport capabilities compared to wildtype. For some vari...

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Bibliographic Details
Main Authors: Thomas J. F. Angenoorth, Julian Maier, Stevan Stankovic, Shreyas Bhat, Sonja Sucic, Michael Freissmuth, Harald H. Sitte, Jae-Won Yang
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cells
Subjects:
4-PBA
µ-pifithrin
17-DMAG
progesterone
corticosterone
pharmacochaperoning
Online Access:https://www.mdpi.com/2073-4409/12/1/39

Internet

https://www.mdpi.com/2073-4409/12/1/39

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