Viral Mimicry of Interleukin-17A by SARS-CoV-2 ORF8

Viral Mimicry of Interleukin-17A by SARS-CoV-2 ORF8

ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection triggers cytokine-mediated inflammation, leading to a myriad of clinical presentations in COVID-19. The SARS-CoV-2 open reading frame 8 (ORF8) is a secreted and rapidly evolving glycoprotein. Patients infected with SARS-...

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Bibliographic Details
Main Authors: Xin Wu, Tian Xia, Woo-Jin Shin, Kwang-Min Yu, Wooram Jung, Alexandra Herrmann, Suan-Sin Foo, Weiqiang Chen, Pengfei Zhang, Jong-Soo Lee, Haryoung Poo, Suzy A. A. Comhair, Lara Jehi, Young Ki Choi, Armin Ensser, Jae U. Jung
Format: Article
Language:English
Published: American Society for Microbiology 2022-04-01
Series:mBio
Subjects:
COVID-19
viral IL-17
inflammation
Online Access:https://journals.asm.org/doi/10.1128/mbio.00402-22

Internet

https://journals.asm.org/doi/10.1128/mbio.00402-22

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