Neuronal Sigma-1 Receptors: Signaling Functions and Protective Roles in Neurodegenerative Diseases

Neuronal Sigma-1 Receptors: Signaling Functions and Protective Roles in Neurodegenerative Diseases

Sigma-1 receptor (S1R) is a multi-functional, ligand-operated protein situated in endoplasmic reticulum (ER) membranes and changes in its function and/or expression have been associated with various neurological disorders including amyotrophic lateral sclerosis/frontotemporal dementia, Alzheimer’s (...

Full description

Bibliographic Details
Main Authors: Daniel A. Ryskamp, Svetlana Korban, Vladimir Zhemkov, Nina Kraskovskaya, Ilya Bezprozvanny
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Neuroscience
Subjects:
synapse
calcium
neuroprotection
Alzheimer’s
Huntington and Parkinson diseases
ALS (amyotrophic lateral sclerosis)
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00862/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2019.00862/full

Similar Items