Dissecting Allele Architecture of Early Onset IBD Using High-Density Genotyping.

The inflammatory bowel diseases (IBD) are common, complex disorders in which genetic and environmental factors are believed to interact leading to chronic inflammatory responses against the gut microbiota. Earlier genetic studies performed in mostly adult population of European descent identified 16...

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Main Authors: David J Cutler, Michael E Zwick, David T Okou, Sampath Prahalad, Thomas Walters, Stephen L Guthery, Marla Dubinsky, Robert Baldassano, Wallace V Crandall, Joel Rosh, James Markowitz, Michael Stephens, Richard Kellermayer, Marian Pfefferkorn, Melvin B Heyman, Neal LeLeiko, David Mack, Dedrick Moulton, Michael D Kappelman, Archana Kumar, Jarod Prince, Promita Bose, Kajari Mondal, Dhanya Ramachandran, John F Bohnsack, Anne M Griffiths, Yael Haberman, Jonah Essers, Susan D Thompson, Bruce Aronow, David J Keljo, Jeffrey S Hyams, Lee A Denson, PRO-KIIDS Research Group, Subra Kugathasan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4476779?pdf=render