Glioblastoma Multiforme Therapy and Mechanisms of Resistance

Glioblastoma multiforme (GBM) is a grade IV brain tumor characterized by a heterogeneous population of cells that are highly infiltrative, angiogenic and resistant to chemotherapy. The current standard of care, comprised of surgical resection followed by radiation and the chemotherapeutic agent temo...

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Bibliographic Details
Main Authors: Yulian P. Ramirez, Jessica L. Weatherbee, Richard T. Wheelhouse, Alonzo H. Ross
Format: Article
Language:English
Published: MDPI AG 2013-11-01
Series:Pharmaceuticals
Subjects:
Online Access:http://www.mdpi.com/1424-8247/6/12/1475