Cell fate regulation governed by p53: Friends or reversible foes in cancer therapy

Abstract Cancer is a leading cause of death worldwide. Targeted therapies aimed at key oncogenic driver mutations in combination with chemotherapy and radiotherapy as well as immunotherapy have benefited cancer patients considerably. Tumor protein p53 (TP53), a crucial tumor suppressor gene encoding...

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Bibliographic Details
Main Authors: Bin Song, Ping Yang, Shuyu Zhang
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Cancer Communications
Subjects:
Online Access:https://doi.org/10.1002/cac2.12520