Electroconvulsive therapy is associated with increased immunoreactivity of neuroplasticity markers in the hippocampus of depressed patients

Abstract Electroconvulsive therapy (ECT) is an effective therapy for depression, but its cellular effects on the human brain remain elusive. In rodents, electroconvulsive shocks increase proliferation and the expression of plasticity markers in the hippocampal dentate gyrus (DG), suggesting increase...

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Bibliographic Details
Main Authors: Dore Loef, Indira Tendolkar, Philip F. P. van Eijndhoven, Jeroen J. M. Hoozemans, Mardien L. Oudega, Annemieke J. M. Rozemuller, Paul J. Lucassen, Annemiek Dols, Anke A. Dijkstra
Format: Article
Language:English
Published: Nature Publishing Group 2023-11-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-023-02658-1