Catalytic atroposelective synthesis of heterobiaryls with vicinal C−C and N−N diaxes via dynamic kinetic resolution

Summary: Reported herein is a highly efficient dynamic kinetic resolution protocol for the atroposelective synthesis of heterobiaryls with vicinal C−C and N−N diaxes. Atropisomers bearing vicinal diaxes mainly exist in o-triaryls, while that of biaryls is highly challenging in terms of the concerted...

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Autori principali: Tian-Jiao Han, Chun-Yan Guan, Na Li, Rui Dong, Li-Ping Xu, Xiao Xiao, Min-Can Wang, Guang-Jian Mei
Natura: Articolo
Lingua:English
Pubblicazione: Elsevier 2023-10-01
Serie:iScience
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Accesso online:http://www.sciencedirect.com/science/article/pii/S2589004223020552