An evidence appraisal of heart organoids in a dish and commensurability to human heart development in vivo
Abstract Stem-cell derived in vitro cardiac models have provided profound insights into mechanisms in cardiac development and disease. Efficient differentiation of specific cardiac cell types from human pluripotent stem cells using a three-step Wnt signaling modulation has been one of the major disc...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-03-01
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Series: | BMC Cardiovascular Disorders |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12872-022-02543-7 |