An evidence appraisal of heart organoids in a dish and commensurability to human heart development in vivo

Abstract Stem-cell derived in vitro cardiac models have provided profound insights into mechanisms in cardiac development and disease. Efficient differentiation of specific cardiac cell types from human pluripotent stem cells using a three-step Wnt signaling modulation has been one of the major disc...

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Bibliographic Details
Main Authors: Dilip Thomas, Vinicio A. de Jesus Perez, Nazish Sayed
Format: Article
Language:English
Published: BMC 2022-03-01
Series:BMC Cardiovascular Disorders
Subjects:
Online Access:https://doi.org/10.1186/s12872-022-02543-7