Endothelial nitric oxide synthase (eNOS) S1176 phosphorylation status governs atherosclerotic lesion formation

ObjectiveWe have previously demonstrated the in vivo importance of the Akt-eNOS substrate-kinase relationship, as defective postnatal angiogenesis characteristic of global Akt1-null mice is rescued when bred to ‘gain-of-function’ eNOS S1176D mutant mice. While multiple studies support the vascular p...

Повний опис

Бібліографічні деталі
Автори: Tung D. Nguyen, Nur-Taz Rahman, William C. Sessa, Monica Y. Lee
Формат: Стаття
Мова:English
Опубліковано: Frontiers Media S.A. 2023-11-01
Серія:Frontiers in Cardiovascular Medicine
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Онлайн доступ:https://www.frontiersin.org/articles/10.3389/fcvm.2023.1279868/full