The Rho1 GTPase controls anillo-septin assembly to facilitate contractile ring closure during cytokinesis

Summary: Animal cell cytokinesis requires activation of the GTPase RhoA (Rho1 in Drosophila), which assembles an F-actin- and myosin II-dependent contractile ring (CR) at the equatorial plasma membrane. CR closure is poorly understood, but involves the multidomain scaffold protein, Anillin. Anillin...

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Bibliographic Details
Main Authors: Sabrya C. Carim, Gilles R.X. Hickson
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422300980X