Based on network pharmacology and molecular docking to explore the protective effect of Epimedii Folium extract on cisplatin-induced intestinal injury in mice

Based on network pharmacology and molecular docking to explore the protective effect of Epimedii Folium extract on cisplatin-induced intestinal injury in mice

Background: Epimedii Folium, as a natural botanical medicine, has been reported to have protective effects on intestinal diseases by modulating multiple signaling pathways. This study aimed to explore the potential targets and molecular mechanisms of Epimedii Folium extract (EFE) against cisplatin-i...

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Bibliographic Details
Main Authors: Juan Xia, Jun-Nan Hu, Zi Wang, En-Bo Cai, Shen Ren, Ying-Ping Wang, Xiu-Juan Lei, Wei Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Pharmacology
Subjects:
Epimedii Folium extract
cisplatin
intestinal injury
network pharmacology
PI3K/Akt signaling pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1040504/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.1040504/full

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