Acquisition of cancer stem cell capacities after spontaneous cell fusion
Abstract Background Cancer stem/Initiating cell (CS/IC) hypothesis argues that CS/ICs are responsible of tumour initiation, drug resistance, metastasis or disease relapse. Their detection in several cancers supports this concept. However, their origin is still misunderstood. Cell fusion is shown to...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-03-01
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Series: | BMC Cancer |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12885-021-07979-2 |