Dysregulated hepatic lipid metabolism and gut microbiota associated with early-stage NAFLD in ASPP2-deficiency mice

Dysregulated hepatic lipid metabolism and gut microbiota associated with early-stage NAFLD in ASPP2-deficiency mice

BackgroundGrowing evidence indicates that lipid metabolism disorders and gut microbiota dysbiosis were related to the progression of non-alcoholic fatty liver disease (NAFLD). Apoptosis-stimulating p53 protein 2 (ASPP2) has been reported to protect against hepatocyte injury by regulating the lipid m...

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Bibliographic Details
Main Authors: Fang Xie, Hang-fei Xu, Jing Zhang, Xiao-ni Liu, Bu-xin Kou, Meng-yin Cai, Jing Wu, Jin-ling Dong, Qing-hua Meng, Yi Wang, Dexi Chen, Yang Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
ASPP2
NAFLD
fatty acid
lipid metabolism
gut microbiota
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.974872/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.974872/full

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