The development of an anti-cancer peptide M1-21 targeting transcription factor FOXM1

The development of an anti-cancer peptide M1-21 targeting transcription factor FOXM1

Abstract Background Transcription factor FOXM1 is a potential target for anti-cancer drug development. An interfering peptide M1-21, targeting FOXM1 and FOXM1-interacting proteins, is developed and its anti-cancer efficacy is evaluated. Methods FOXM1 C-terminus-binding peptides are screened by in si...

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Bibliographic Details
Main Authors: Haojie Cheng, Jie Yuan, Chaozhu Pei, Min Ouyang, Huitong Bu, Yan Chen, Xiaoqin Huang, Zhenwang Zhang, Li Yu, Yongjun Tan
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Cell & Bioscience
Subjects:
M1-21
D-retro-inverso (DRI) peptide
Transcription factor FOXM1
Interfering peptide
Cancer treatment
Online Access:https://doi.org/10.1186/s13578-023-01059-7

Internet

https://doi.org/10.1186/s13578-023-01059-7

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