Multisite phosphorylation of the guanine nucleotide exchange factor Cdc24 during yeast cell polarization.
BACKGROUND:Cell polarization is essential for processes such as cell migration and asymmetric cell division. A common regulator of cell polarization in most eukaryotic cells is the conserved Rho GTPase, Cdc42. In budding yeast, Cdc42 is activated by a single guanine nucleotide exchange factor, Cdc24...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2009-08-01
|
| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC2718613?pdf=render |