Cannabinoid 1/2 Receptor Activation Induces Strain-Dependent Behavioral and Neurochemical Changes in Genetic Absence Epilepsy Rats From Strasbourg and Non-epileptic Control Rats

Cannabinoid 1/2 Receptor Activation Induces Strain-Dependent Behavioral and Neurochemical Changes in Genetic Absence Epilepsy Rats From Strasbourg and Non-epileptic Control Rats

Childhood absence epilepsy (CAE) is characterized by absence seizures, which are episodes of lack of consciousness accompanied by electrographic spike-wave discharges. About 60% of children and adolescents with absence seizures are affected by major neuropsychological comorbidities, including anxiet...

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Bibliographic Details
Main Authors: Philippe De Deurwaerdère, Maurizio Casarrubea, Daniel Cassar, Manuela Radic, Emilie Puginier, Abdeslam Chagraoui, Giuseppe Crescimanno, Vincenzo Crunelli, Giuseppe Di Giovanni
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
cannabinoid receptors
CB1
CB2
strain-dependent effects
high-pressure liquid chromatography
thalamus
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2022.886033/full

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https://www.frontiersin.org/articles/10.3389/fncel.2022.886033/full

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