Synthesis, in vitro analysis and molecular docking study of novel benzoxazole-based oxazole derivatives for the treatment of Alzheimer’s disease

Synthesis, in vitro analysis and molecular docking study of novel benzoxazole-based oxazole derivatives for the treatment of Alzheimer’s disease

Alzheimer's disease (AD) is treated by targeting cholinesterase enzymes like acetylcholinesterase and butyrylcholinesterase, and these enzymes' inhibitors serve as important tools for treatment of alzheimer diseases. Hybrid analogues with a 1,3-oxazole moiety based on benzoxazole were desi...

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Bibliographic Details
Main Authors: Rafaqat Hussain, Fazal Rahim, Wajid Rehman, Shoaib Khan, Liaqat Rasheed, Aneela Maalik, Muhammad Taha, Mohammed M. Alanazi, Ashwag S. Alanazi, Imran Khan, Syed Adnan Ali Shah
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Arabian Journal of Chemistry
Subjects:
Synthesis
AChE & BuChE inhibitors
1,3-Oxazole
Benzoxazole
Molecular docking
SAR
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535223007062

Internet

http://www.sciencedirect.com/science/article/pii/S1878535223007062

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