Origin, Diversity, and Multiple Roles of Enzymes with Metallo-β-Lactamase Fold from Different Organisms

Origin, Diversity, and Multiple Roles of Enzymes with Metallo-β-Lactamase Fold from Different Organisms

β-lactamase enzymes have generated significant interest due to their ability to confer resistance to the most commonly used family of antibiotics in human medicine. Among these enzymes, the class B β-lactamases are members of a superfamily of metallo-β-lactamase (MβL) fold proteins which are charact...

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Bibliographic Details
Main Authors: Seydina M. Diene, Pierre Pontarotti, Saïd Azza, Nicholas Armstrong, Lucile Pinault, Eric Chabrière, Philippe Colson, Jean-Marc Rolain, Didier Raoult
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Cells
Subjects:
metallo-β-lactamase (MβL) fold proteins
multifunctional enzymes
antibiotic-hydrolysing activity
nuclease
ribonuclease
lactonase
Online Access:https://www.mdpi.com/2073-4409/12/13/1752

Internet

https://www.mdpi.com/2073-4409/12/13/1752

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