PDGF-D-induced immunoproteasome activation and cell-cell interactions

Platelet-derived growth factor-D (PDGF-D) is abundantly expressed in ocular diseases. Yet, it remains unknown whether and how PDGF-D affects ocular cells or cell-cell interactions in the eye. In this study, using single-cell RNA sequencing (scRNA-seq) and a mouse model of PDGF-D overexpression in re...

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Bibliographic Details
Main Authors: Jianing Zhang, Wanhong Li, Zhen Xiong, Juanhua Zhu, Xiangrong Ren, Shasha Wang, Haiqing Kuang, Xianchai Lin, Antonio Mora, Xuri Li
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037023001460