Regulation of ATP levels in Escherichia coli using CRISPR interference for enhanced pinocembrin production

Regulation of ATP levels in Escherichia coli using CRISPR interference for enhanced pinocembrin production

Abstract Background Microbial biosynthesis of natural products holds promise for preclinical studies and treating diseases. For instance, pinocembrin is a natural flavonoid with important pharmacologic characteristics and is widely used in preclinical studies. However, high yield of natural products...

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Bibliographic Details
Main Authors: Sha Tao, Ying Qian, Xin Wang, Weijia Cao, Weichao Ma, Kequan Chen, Pingkai Ouyang
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Microbial Cell Factories
Subjects:
Flavonoids
ATP
CRISPRi
Pinocembrin
Online Access:http://link.springer.com/article/10.1186/s12934-018-0995-7

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http://link.springer.com/article/10.1186/s12934-018-0995-7

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