HDAC Inhibitor Titration of Transcription and Axolotl Tail Regeneration

HDAC Inhibitor Titration of Transcription and Axolotl Tail Regeneration

New patterns of gene expression are enacted and regulated during tissue regeneration. Histone deacetylases (HDACs) regulate gene expression by removing acetylated lysine residues from histones and proteins that function directly or indirectly in transcriptional regulation. Previously we showed that...

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Bibliographic Details
Main Authors: S. Randal Voss, Jeramiah J. Smith, Raissa F. Cecil, Mirindi Kabangu, Timothy J. Duerr, James R. Monaghan, Nataliya Timoshevskaya, Larissa V. Ponomareva, Jon S. Thorson, Alan Veliz-Cuba, David Murrugarra
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
HDAC
axolotl (Ambystoma mexicanum)
regeneration
romidepsin
transcription
single nuclei RNA-seq
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.767377/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.767377/full

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