Endogenous Coriobacteriaceae enriched by a high-fat diet promotes colorectal tumorigenesis through the CPT1A-ERK axis

Endogenous Coriobacteriaceae enriched by a high-fat diet promotes colorectal tumorigenesis through the CPT1A-ERK axis

Abstract A high-fat diet (HFD) may be linked to an increased colorectal cancer (CRC) risk. Stem cell proliferation and adipokine release under inflammatory and obese conditions are the main factors regulating CRC progression. Furthermore, alterations in intestinal flora have been linked to tumorigen...

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Bibliographic Details
Main Authors: Qiulin Tang, Huixi Huang, Huanji Xu, Hongwei Xia, Chenliang Zhang, Di Ye, Feng Bi
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:npj Biofilms and Microbiomes
Online Access:https://doi.org/10.1038/s41522-023-00472-7

Internet

https://doi.org/10.1038/s41522-023-00472-7

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