An alternating GluN1-2-1-2 subunit arrangement in mature NMDA receptors.

NMDA receptors (NMDARs) form glutamate-gated ion channels that play a critical role in CNS physiology and pathology. Together with AMPA and kainate receptors, NMDARs are known to operate as tetrameric complexes with four membrane-embedded subunits associating to form a single central ion-conducting...

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Bibliographic Details
Main Authors: Morgane Riou, David Stroebel, J Michael Edwardson, Pierre Paoletti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3320871?pdf=render