SEPT2 crotonylation promotes metastasis and recurrence in hepatocellular carcinoma and is associated with poor survival

SEPT2 crotonylation promotes metastasis and recurrence in hepatocellular carcinoma and is associated with poor survival

Abstract Background Hepatocellular carcinoma (HCC) metastasis and recurrence lead to therapy failure, which are closely associated with the proteome. However, the role of post-translational modification (PTM) in HCC, especially for the recently discovered lysine crotonylation (Kcr), is elusive. Resu...

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Bibliographic Details
Main Authors: Xin-yue Zhang, Ze-xian Liu, Yi-fan Zhang, Li-xia Xu, Meng-ke Chen, Yu-feng Zhou, Jun Yu, Xiao-xing Li, Ning Zhang
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Cell & Bioscience
Subjects:
Hepatocellular carcinoma
Posttranslational modification
Crotonylation
SEPT2
Prognosis and recurrence marker
Online Access:https://doi.org/10.1186/s13578-023-00996-7

Internet

https://doi.org/10.1186/s13578-023-00996-7

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