Comparison of monocytic cell lines U937 and THP-1 as macrophage models for in vitro studies

Comparison of monocytic cell lines U937 and THP-1 as macrophage models for in vitro studies

Understanding macrophage biology can improve comprehension of diverse biological processes and provide insights into novel therapeutic immunomodulatory strategies. Due to limited yield and technical difficulty in isolating primary macrophages, in vitro studies commonly use monocytes as precursor cel...

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Bibliographic Details
Main Authors: Camyla Rodrigues Nascimento, Natalie Ap Rodrigues Fernandes, Laura Andrea Gonzalez Maldonado, Carlos Rossa Junior
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Biochemistry and Biophysics Reports
Subjects:
Macrophage
Gene expression
THP-1 cells
U937 cells
Phenotype
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580822001832

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http://www.sciencedirect.com/science/article/pii/S2405580822001832

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