Histone Deacetylases in the Inflamed Intestinal Epithelium—Promises of New Therapeutic Strategies

The intestinal epithelium is a complex, dynamic barrier that separates luminal contents from the immune compartment while mediating nutrient absorption and controlled passage of antigens to convey oral tolerance. A compromised epithelial barrier often leads to inflammation because immune cells in th...

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Bibliographic Details
Main Authors: Lorenz Gerbeth, Rainer Glauben
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.655956/full