ACTL6A protects gastric cancer cells against ferroptosis through induction of glutathione synthesis

ACTL6A protects gastric cancer cells against ferroptosis through induction of glutathione synthesis

Abstract Gastric cancer (GC), one of the most common malignant tumors in the world, exhibits a rapid metastasis rate and causes high mortality. Diagnostic markers and potential therapeutic targets for GCs are urgently needed. Here we show that Actin-like protein 6 A (ACTL6A), encoding an SWI/SNF sub...

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Bibliographic Details
Main Authors: Ziqing Yang, Shaomin Zou, Yijing Zhang, Jieping Zhang, Peng Zhang, Lishi Xiao, Yunling Xie, Manqi Meng, Junyan Feng, Liang Kang, Mong-Hong Lee, Lekun Fang
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-39901-8

Internet

https://doi.org/10.1038/s41467-023-39901-8

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