Helios expressing regulatory T cells are correlated with decreased IL-2 producing CD8 T cells and antibody diversity in Mozambican individuals living chronically with HIV-1

Helios expressing regulatory T cells are correlated with decreased IL-2 producing CD8 T cells and antibody diversity in Mozambican individuals living chronically with HIV-1

Abstract Background Human immunodeficiency virus type 1 (HIV-1) causes impairment of T and B cell responses, which begins during the acute phase of infection and is not completely restored by antiretroviral treatment. Regulatory T cell (Tregs) can improve overall disease outcome by controlling chron...

Full description

Bibliographic Details
Main Authors: Raquel Matavele Chissumba, Cacildo Magul, Rosa Macamo, Vânia Monteiro, Maria Enosse, Ivalda Macicame, Victória Cumbane, Nilesh Bhatt, Edna Viegas, Michelle Imbach, Leigh Anne Eller, Christina S. Polyak, Luc Kestens, for the RV363 Study Group
Format: Article
Language:English
Published: BMC 2022-03-01
Series:BMC Immunology
Subjects:
Seronegativity
Tregs
HIV chronic infection
Helios
Online Access:https://doi.org/10.1186/s12865-022-00487-3

Internet

https://doi.org/10.1186/s12865-022-00487-3

Similar Items