Prediction of dynamic allostery for the transmembrane domain of the sweet taste receptor subunit, TAS1R3

Prediction of dynamic allostery for the transmembrane domain of the sweet taste receptor subunit, TAS1R3

Molecular dynamics simulations and functional assays of the transmembrane domain of the sweet taste receptor subunit, TAS1R3 reveal mechanisms on the allostery of sweet receptor activation or inactivation and pH-dependent sensitivity to saccharin.

Bibliographic Details
Main Authors: Keisuke Sanematsu, Masato Yamamoto, Yuki Nagasato, Yuko Kawabata, Yu Watanabe, Shusuke Iwata, Shingo Takai, Kiyoshi Toko, Toshiro Matsui, Naohisa Wada, Noriatsu Shigemura
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-04705-5

Internet

https://doi.org/10.1038/s42003-023-04705-5

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