Expression of Nectin-4 in Variant Histologies of Bladder Cancer and Its Prognostic Value—Need for Biomarker Testing in High-Risk Patients?

Expression of Nectin-4 in Variant Histologies of Bladder Cancer and Its Prognostic Value—Need for Biomarker Testing in High-Risk Patients?

Variant histologies of bladder cancer (BC) often present with advanced tumor stage and the status of perioperative therapy is unclear. Thereby, squamous cell carcinoma (SCC), adenocarcinoma (ADENO), and sarcomatoid urothelial carcinoma (SARCO) are the most frequent variants. Nectin-4 has emerged as...

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Bibliographic Details
Main Authors: Severin Rodler, Lennert Eismann, Boris Schlenker, Jozefina Casuscelli, Isabel Brinkmann, Andrea Sendelhofert, Raphaela Waidelich, Alexander Buchner, Christian Stief, Gerald Bastian Schulz, Stephan Ledderose
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cancers
Subjects:
Nectin-4
squamous cell carcinoma
neoadjuvant therapy
adjuvant therapy
antibody–drug conjugate
Online Access:https://www.mdpi.com/2072-6694/14/18/4411

Internet

https://www.mdpi.com/2072-6694/14/18/4411

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