Correlation Analyses between Histological Staging and Molecular Alterations in Tumor-Derived and Cell-Free DNA of Early-Stage Primary Cutaneous Melanoma

Correlation Analyses between Histological Staging and Molecular Alterations in Tumor-Derived and Cell-Free DNA of Early-Stage Primary Cutaneous Melanoma

Here, we investigate the correlation and statistical analyses between histological staging and molecular alterations in tumor-derived (tdDNA) and cell-free DNA (cfDNA) obtained from early-stage primary cutaneous melanoma (PCM) patients using digital PCR (dPCR) for the detection of the <i>BRAF&...

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Bibliographic Details
Main Authors: Szilvia Lilla Csoma, Kristóf Madarász, Yi Che Chang Chien, Gabriella Emri, Judit Bedekovics, Gábor Méhes, Attila Mokánszki
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Cancers
Subjects:
primary cutaneous melanoma
Breslow depth
Clark level
somatic variant allele frequency
cell-free DNA
<i>BRAF</i> gene mutation
Online Access:https://www.mdpi.com/2072-6694/15/21/5141

Internet

https://www.mdpi.com/2072-6694/15/21/5141

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