Pioneer transcription factors are associated with the modulation of DNA methylation patterns across cancers

Pioneer transcription factors are associated with the modulation of DNA methylation patterns across cancers

Abstract Methylation of cytosines on DNA is a prominent modification associated with gene expression regulation. Aberrant DNA methylation patterns have recurrently been linked to dysregulation of the regulatory program in cancer cells. To shed light on the underlying molecular mechanism driving this...

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Bibliographic Details
Main Authors: Roza Berhanu Lemma, Thomas Fleischer, Emily Martinsen, Marit Ledsaak, Vessela Kristensen, Ragnhild Eskeland, Odd Stokke Gabrielsen, Anthony Mathelier
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Epigenetics & Chromatin
Online Access:https://doi.org/10.1186/s13072-022-00444-9

Internet

https://doi.org/10.1186/s13072-022-00444-9

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