Inter-channel scaffolding of presynaptic CaV2.2 via the C terminal PDZ ligand domain
Summary Calcium entry through CaV2.2 calcium channels clustered at the active zone (AZ) of the presynaptic nerve terminal gates synaptic vesicle (SV) fusion and the discharge of neurotransmitters, but the mechanism of channel scaffolding remains poorly understood. Recent studies have implicated the...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2013-04-01
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Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/2/5/492 |