Shared enhancer gene regulatory networks between wound and oncogenic programs

Shared enhancer gene regulatory networks between wound and oncogenic programs

Wound response programs are often activated during neoplastic growth in tumors. In both wound repair and tumor growth, cells respond to acute stress and balance the activation of multiple programs, including apoptosis, proliferation, and cell migration. Central to those responses are the activation...

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Bibliographic Details
Main Authors: Swann Floc'hlay, Ramya Balaji, Dimitrije Stanković, Valerie M Christiaens, Carmen Bravo González-Blas, Seppe De Winter, Gert J Hulselmans, Maxime De Waegeneer, Xiaojiang Quan, Duygu Koldere, Mardelle Atkins, Georg Halder, Mirka Uhlirova, Anne-Kathrin Classen, Stein Aerts
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-05-01
Series:eLife
Subjects:
wound response
enhancer
cancer
gene regulatory network
chromatin accessibility
single-cell multiomics
Online Access:https://elifesciences.org/articles/81173

Internet

https://elifesciences.org/articles/81173

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