Characteristics of Skin Deposition of Itraconazole Solubilized in Cream Formulation

Itraconazole (ITZ) is an anti-fungal agent generally used to treat cutaneous mycoses. For efficient delivery of ITZ to the skin tissues, an oil-in-water (O/W) cream formulation was developed. The O/W cream base was designed based on the solubility measurement of ITZ in various excipients. A physical...

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Bibliographic Details
Main Authors: Hyeongmin Kim, Sukkyun Jung, Sooho Yeo, Dohyun Kim, Young Chae Na, Gyiae Yun, Jaehwi Lee
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/11/4/195