The roles of protocadherin-7 in colorectal cancer cells on cell proliferation and its chemoresistance

Despite the high mutation frequencies of KRAS, NRAS, and BRAF in colorectal cancer (CRC), there are no effective and reliable inhibitors for these biomarkers. Protocadherin-7 (PCDH7) is regarded as a potentially targetable surface molecule in cancer cells and plays an important role in their prolife...

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Bibliographic Details
Main Authors: Zhibao Zheng, Na Luan, Kai Tu, Feiyan Liu, Jianwei Wang, Jianguo Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1072033/full