Effect of flow change on brain injury during an experimental model of differential hypoxaemia in cardiogenic shock supported by extracorporeal membrane oxygenation

Abstract Differential hypoxaemia (DH) is common in patients supported by femoral veno-arterial extracorporeal membrane oxygenation (V-A ECMO) and can cause cerebral hypoxaemia. To date, no models have studied the direct impact of flow on cerebral damage. We investigated the impact of V-A ECMO flow o...

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Bibliographic Details
Main Authors: Sacha Rozencwajg, Silver Heinsar, Karin Wildi, Jae‐Seung Jung, Sebastiano Maria Colombo, Chiara Palmieri, Kei Sato, Carmen Ainola, Xiaomeng Wang, Gabriella Abbate, Noriko Sato, Wayne B. Dyer, Samantha Livingstone, Leticia Helms, Nicole Bartnikowski, Mahe Bouquet, Margaret R. Passmore, Kieran Hyslop, Bruno Vidal, Janice D. Reid, Daniel McGuire, Emily S. Wilson, Indrek Rätsep, Roberto Lorusso, Matthieu Schmidt, Jacky Y. Suen, Gianluigi Li Bassi, John F. Fraser
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-30226-6