Subcellular Compartmentalization and Trafficking of the Biosynthetic Machinery for Fungal Melanin

Protection by melanin depends on its subcellular location. Although most filamentous fungi synthesize melanin via a polyketide synthase pathway, where and how melanin biosynthesis occurs and how it is deposited as extracellular granules remain elusive. Using a forward genetic screen in the pathogen...

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Bibliographic Details
Main Authors: Srijana Upadhyay, Xinping Xu, David Lowry, Jennifer C. Jackson, Robert W. Roberson, Xiaorong Lin
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716301802