Smooth muscle cells largely develop independently of functional hemogenic endothelium

Vascular smooth muscle cells represent a major component of the cardiovascular system. In vitro studies have shown that FLK1+ cells derived from embryonic stem (ES) cells can differentiate into both endothelial and smooth muscle cells. These FLK1+ cells also contain a mesodermal precursor, the heman...

Full description

Bibliographic Details
Main Authors: Monika Stefanska, Guilherme Costa, Michael Lie-a-Ling, Valerie Kouskoff, Georges Lacaud
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506113001591