The zinc transporter SLC39A14/ZIP14 controls G-protein coupled receptor-mediated signaling required for systemic growth.

Aberrant zinc (Zn) homeostasis is associated with abnormal control of mammalian growth, although the molecular mechanisms of Zn's roles in regulating systemic growth remain to be clarified. Here we report that the cell membrane-localized Zn transporter SLC39A14 controls G-protein coupled recept...

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Bibliographic Details
Main Authors: Shintaro Hojyo, Toshiyuki Fukada, Shinji Shimoda, Wakana Ohashi, Bum-Ho Bin, Haruhiko Koseki, Toshio Hirano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3062567?pdf=render