Iodine-131 dose dependent gene expression in thyroid cancers and corresponding normal tissues following the Chernobyl accident.

The strong and consistent relationship between irradiation at a young age and subsequent thyroid cancer provides an excellent model for studying radiation carcinogenesis in humans. We thus evaluated differential gene expression in thyroid tissue in relation to iodine-131 (I-131) doses received from...

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Bibliographic Details
Main Authors: Michael Abend, Ruth M Pfeiffer, Christian Ruf, Maureen Hatch, Tetiana I Bogdanova, Mykola D Tronko, Armin Riecke, Julia Hartmann, Viktor Meineke, Houda Boukheris, Alice J Sigurdson, Kiyohiko Mabuchi, Alina V Brenner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3405097?pdf=render