Innovative in vivo rat model for global cerebral hypoxia: a new approach to investigate therapeutic and preventive drugs

Introduction: Severe acute global cerebral hypoxia can lead to significant disability in humans. Although different animal models have been described to study hypoxia, there is no endogenous model that considers hypoxia and its effect on the brain as an independent factor. Thus, we developed a minim...

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Bibliographic Details
Main Authors: Sarah Stahlke, Jonas Frai, Johanna Franziska Busse, Veronika Matschke, Carsten Theiss, Thomas Weber, Jennifer Herzog-Niescery
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2024.1293247/full