Predictive value of CD8+ T cell and CD4/CD8 ratio at two years of successful ART in the risk of AIDS and non-AIDS events

Predictive value of CD8+ T cell and CD4/CD8 ratio at two years of successful ART in the risk of AIDS and non-AIDS events

Summary: Background: While increased CD8 counts and low CD4/CD8 ratio during treated HIV correlate with immunosenescence, their additional predictive values to identify individuals with HIV at higher risk of clinical events remain controversial. Methods: We selected treatment-naive individuals init...

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Bibliographic Details
Main Authors: Sergio Serrano-Villar, Kunling Wu, Peter W. Hunt, Judith J. Lok, Raquel Ron, Talía Sainz, Santiago Moreno, Steven G. Deeks, Ronald J. Bosch
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:EBioMedicine
Subjects:
HIV
Antiretroviral therapy
CD4+ T cells
CD8+ T cells
CD4/CD8 ratio
Clinical outcomes
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396422002535

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http://www.sciencedirect.com/science/article/pii/S2352396422002535

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