mGluR-dependent plasticity in rodent models of Alzheimer’s disease

mGluR-dependent plasticity in rodent models of Alzheimer’s disease

Long-term potentiation (LTP) and depression (LTD) are currently the most comprehensive models of synaptic plasticity models to subserve learning and memory. In the CA1 region of the hippocampus LTP and LTD can be induced by the activation of either NMDA receptors or mGluR5 metabotropic glutamate rec...

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Bibliographic Details
Main Authors: Gonzalo Valdivia, Alvaro O. Ardiles, Abimbola Idowu, Claudia Salazar, Hey-Kyoung Lee, Michela Gallagher, Adrian G. Palacios, Alfredo Kirkwood
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
LTP (long term potentiation)
LTD (long term pepression)
mGluR5
Alzheimer’s disease
aging
Online Access:https://www.frontiersin.org/articles/10.3389/fnsyn.2023.1123294/full

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https://www.frontiersin.org/articles/10.3389/fnsyn.2023.1123294/full

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