Herpes Simplex Virus 1 Entry Glycoproteins Form Complexes before and during Membrane Fusion

ABSTRACT Herpesviruses—ubiquitous pathogens that cause persistent infections—have some of the most complex cell entry mechanisms. Entry of the prototypical herpes simplex virus 1 (HSV-1) requires coordinated efforts of 4 glycoproteins, gB, gD, gH, and gL. The current model posits that the glycoprote...

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Bibliographic Details
Main Authors: Zemplen Pataki, Andrea Rebolledo Viveros, Ekaterina E. Heldwein
Format: Article
Language:English
Published: American Society for Microbiology 2022-10-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mbio.02039-22