Metabolic constraints on the evolution of antibiotic resistance
Abstract Despite our continuous improvement in understanding antibiotic resistance, the interplay between natural selection of resistance mutations and the environment remains unclear. To investigate the role of bacterial metabolism in constraining the evolution of antibiotic resistance, we evolved...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Springer Nature
2017-03-01
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Series: | Molecular Systems Biology |
Subjects: | |
Online Access: | https://doi.org/10.15252/msb.20167028 |