Evaluation of Everolimus Activity against <i>Mycobacterium tuberculosis</i> Using In Vitro Models of Infection

Evaluation of Everolimus Activity against <i>Mycobacterium tuberculosis</i> Using In Vitro Models of Infection

Even though Everolimus has been investigated in a phase II randomized trial as a host-directed therapy (HDT) to treat tuberculosis (TB), an oncological patient treated with Everolimus for a neuroendocrine pancreatic neoplasia developed active TB twice and a non-tuberculous mycobacterial (NTM) infect...

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Bibliographic Details
Main Authors: Delia Mercedes Bianco, Flavio De Maio, Giulia Santarelli, Ivana Palucci, Alessandro Salustri, Giada Bianchetti, Giuseppe Maulucci, Franco Citterio, Maurizio Sanguinetti, Enrica Tamburrini, Michela Sali, Giovanni Delogu
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Antibiotics
Subjects:
latent tuberculosis infection
host-directed therapies
Everolimus
mTOR inhibitors
Online Access:https://www.mdpi.com/2079-6382/12/1/171

Internet

https://www.mdpi.com/2079-6382/12/1/171

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