Genome editing in rice mediated by miniature size Cas nuclease SpCas12f

Genome editing in rice mediated by miniature size Cas nuclease SpCas12f

Cas9 derived from Streptococcus pyogenes (SpCas9) is used widely in genome editing using the CRISPR-Cas system due to its high activity, but is a relatively large molecule (1,368 amino acid (a.a.) residues). Recently, targeted mutagenesis in human cells and maize using Cas12f derived from Syntrophom...

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Bibliographic Details
Main Authors: Satoru Sukegawa, Osamu Nureki, Seiichi Toki, Hiroaki Saika
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Genome Editing
Subjects:
CRISPR-Cas12f
deletion
genome editing
Oryza sativa
targeted mutagenesis
syntrophomonas palmitatica
Online Access:https://www.frontiersin.org/articles/10.3389/fgeed.2023.1138843/full

Internet

https://www.frontiersin.org/articles/10.3389/fgeed.2023.1138843/full

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